One rainy afternoon in Istanbul, a woman walks into a doctor's surgery. 'I need to have an abortion', she announces. She is 19 years old and unmarried. What happens that afternoon will change her life.

Twenty years later, Asya Kazanci lives with her extended family in Istanbul. Due to a mysterious family curse, all the Kaznci men die in their early 40s, so it is a house of women, among them Asya's beautiful, rebellious mother, Zeliha, who runs a tattoo parlour; Banu, who has newly discovered herself as clairvoyant; and Feride, a hypochondriac obsessed with impending disaster. And when Asya's Armenian American cousin Armanoush comes to stay, long hidden family secrets connected with Turkey's turbulent past begin to emerge.